One of the most embarrassing men’s health problems is premature ejaculation. The condition is described as incapability to hold the orgasm for the required time. While most of men can perform sexual act up to their and their partners’ satisfactory level, there are few who find it difficult to stay up to a particular time of period. Dapoxetine is one such drug that helps in getting rid of premature ejaculation (PE) in men.
A man suffering from premature ejaculation would not last long in performing sexual activities or lovemaking for the time he is expected to. Having said this, a little stimulation or arousing makes him ejaculate the semen and the act is considered finished. This is because after ejaculating the fluid, the penis starts becoming flaccid due to reverse cycle of filling the blood. It is for this reason, a man has to retain the urge and ejaculate after his partner and he himself feel it to come.
How does Dapoxetine work?
The molecule of dapoxetine comes under the category called SSRI (Selective Serotonin Reuptake Inhibitors). These drugs are used in treating premature ejaculation (PE) because they have rapid onset of action. The effect is maximum within a couple of hours and it can also eliminated from the body in 24 hr.
In men, ejaculation comes from the reflex which is intermediated by the sympathetic nervous system. The ejaculation happens once the body reaches to a particular threshold of sexual stimulation. The sensory nerve cells present in the spinal cord gets charged and they send nerve impulses to the brain. The brain, as a response, sends a message back to motor neurons which control the muscles present in the male organ.
The process of ejaculation is said to get influenced by serotonin. Serotonin is a unique brain chemical (called neurotransmitter) which is responsible to transmit signals across the body. With the help of such chemicals, the brain communicates with rest of the body parts.
Premature ejaculation could be due to several reasons but one of the reasons is reduced levels of serotonin in some part of the brain that deals with sexual stimulation and ejaculation. Reduced amounts of serotonin does not allow the brain to effectively communicate with male organ and as a result, the man comes earlier than required.
Dapoxetine typically blocks the reuptake of serotonin from small gaps between the nerve cells known as the synapse. In case of pre-synaptic, if serotonin reuptake by the first nerve cell is blocked off, this would result in retention of more serotonin which can receive nerve cell (post-synaptic) messages. All in all, the nerve cells would communicate with each other for quite long time. This mechanism of the drug dapoxetine assists in prolonging the capability to keep up sexual acts or lovemaking without the man ejaculating earlier. That said, he can maintain or control over orgasm for longer.
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