Product Code : AKI-AC-706
Product Desciption :
Exemestane is an oral steroidal aromatise inhibitor used in the adjuvant treatment of hormonally-responsive breast cancer in postmenopausal women. An aim in the treatment of hormone-receptor-positive patients in preventing recurrence is to lower estrogen levels that this breast cancer thrives on.
The main source of estrogen is the ovaries in premenopausal women, while in post-menopausal women most of the body's estrogen is produced in the adrenal gland from the conversion of androgens into estrogen by the aromatase enzyme. Exemestane tablets are an irreversible, steroidal aromatase inactivator, structurally related to the natural substrate androstenedione.
Exemestane is an irreversible selective aromatase inhibitor which acts as a false substrate for the aromatase enzyme, forming an intermediate that binds irreversibly to the active site causing its inactivation.
It also lowers circulating oestrogens in estrogen-dependent breast carcinoma.
Uses of Exemestane Tablets
Exemestane is an oral medication prescribed to treat breast cancer in post-menopausal women.
It operates by reducing estrogen levels to stop or slow the growth of tumours that are thought to use this hormone to grow.
Dosage and Administration
Strictly use Exemestane as prescribed by your physician to get the best results.
Your dosage and frequency of administration will be determined based on your symptoms and current health condition.
Swallow the tablets whole and unaltered with a full glass of water after a meal or snack to prevent an upset stomach.
Do not alter the form of the medication by chewing, splitting, or dissolving them in water as this can destroy the contents or change their effects.
Exemestane tablets should be used by women who have not gone through menopause, pregnant, breastfeeding, or lactose intolerant. Also disclose if you have osteoporosis, decreased liver function, or decreased kidney function to make sure any necessary adjustments are made to your dosage.